human somatic cells

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    人体细胞

数据更新时间:2026-08-19 17:14:14
1、

Telomerase activity was found to be absent in most normal human somatic cells and S. cerevisiae but present in over 90% of cancer cells.

正常人体细胞(非生殖细胞)及酿酒酵母细胞中端粒酶活性的表达很低,用一般的方法几乎检测不到,在90%以上的恶性肿瘤细胞中可检测到端粒酶活性。

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3、

In human somatic cells, telomeres shorten by 30 to 200 bp with each cell division. When telomeres were shortened to some threshold value, cell senescence or apoptosis was triggered.

随着细胞分裂端粒每次缩短30~200bp,当端粒缩短到某临界长度时,细胞则发生衰老或凋亡。

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4、

Recent advances indicate that the expression of telomerase activity is repressed in most normal human somatic cells but is reactivated during the carcinogenesis of most human cells.

最近研究表明,端粒酶在绝大多数肿瘤细胞中表达活性,而在正常人体细胞中几乎无端粒酶活性表达。

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5、

The reverse transcriptase telomerase is able to maintain stable telomeric length and essential for the unlimited proliferation of tumor cells. Telomerase activity has been detected in 85-90% of human tumors and tumor-derived cell lines but not in most human somatic cells.

端粒酶表达于85%以上的肿瘤细胞中,能够维持细胞中端粒的长度,对永生化细胞的增殖具有重要作用,而在大多数人正常体细胞中却没有表达。

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